From the moment of birth, the human body becomes colonized with numerous microorganisms acquired from the birth canal and the surrounding environment. Perturbation of the microbial balance, a state known as dysbiosis, can result in pro-inflammatory responses as well as loss of metabolic equilibrium.

There are myriad manifestations of rheumatoid arthritis (RA) and its treatment that manifest in the skin. The skin is the most commonly involved extra-articular site in RA. As access to a dermatologist often may be limited, and as an ever-increasing number of biologic agents with adverse skin effects are prescribed by rheumatologists, the need for rheumatologists to comfortably and reliably recognize and treat these skin conditions has never been as important.

Clinicians who treat pain have noted that the response to opioids varies widely among patients, with opioid dose requirements varying in the clinical setting by as much as 40-fold.

PRINTER-FRIENDLY VERSION AT rheumatologypracticenews.comthose of other central nervous system (CNS) depressants. “Numerous studies have shown that cannabis impairs road-driving performance and have linked cannabis use with increased incidents of road traffic accidents … a large proportion of such drivers have not taken alcohol or have concentrations below the legal limit.”13 Furthermore, “there is sufficient consistency and coherence from experimental studies and studies of canannabinoid levels among accident victims… to conclude that there is an increased risk of motor vehicle accidents among ...

Not long ago, FDA-approved pharmacologic options for treating patients with osteoporosis were limited.